Health and disease are not determined at the organ or organ systems but at the millions of cells they make up. The action of energy homeostasis is crucial to the fate of cells because all cellular activities are strongly dependent on the balance between catabolic and anabolic pathways. Also called "cellular power plants", mitochondria generate the energy and signals needed for life. When mitochondria do not work properly, they can cause serious illnesses that affect different body systems.
Experimental studies so far have concluded that mitochondrial vulnerability to stress can be influenced by a wide range of factors, including eating and eating habits, personalized nutrition can be considered as a preventive and therapeutic method.
Randomized controlled trials represent the best study models that could provide direct evidence of a causal relationship; however, there are methodological difficulties in applying and maintaining evidence of lifestyle for a sufficiently long period.
The present presentation is an attempt to highlight the effects of psychological stress in the physical area, implicitly on health. According to a number of new articles and studies, a key piece of the puzzle lies in specialized cellular structures, known as mitochondria.
Despite the current awareness of the role of nutrition in stress management as well as in serious pathologies, there is still an inappropriate application of research results in clinical practice. The proposal is to create preventive research teams demonstrating the real impact on health through lifestyle interventions, implicit in the cellular energy level