Myasthenia Gravis is a chronic autoimmune disease characterized by fluctuating muscle weakness, caused by a deficiency in the transmission of signals between nerves and muscles.
Causes: Myasthenia Gravis is an autoimmune disease caused by the production of antibodies that block or destroy acetylcholine receptors at the neuromuscular junction, affecting the transmission of nerve signals to the muscles.
Symptoms: Symptoms include progressive muscle weakness, which worsens after activity and can affect the muscles of the face, neck, arms and eyes, causing double vision, drooping eyelids and difficulty swallowing.
Diagnosis: Diagnosis is based on a combination of clinical evaluation, specific antibody tests and repetitive stimulation tests to assess muscle function.
Integrative Treatment: Integrative treatment combines classic medication (cholinesterase inhibitors, immunosuppressants), plasma therapies (plasmapheresis or intravenous immunoglobulins) and measures such as a balanced diet, physiotherapy and relaxation techniques to support overall health.
H2: What is myasthenia gravis?
Myasthenia gravis is a rare autoimmune disease that affects the normal functioning of muscles, characterized by muscle weakness that worsens with physical activity and improves after rest. This condition occurs when the immune system attacks acetylcholine receptors, a substance essential for transmitting signals from nerves to muscles.
H2: How does myasthenia gravis affect the body?
Myasthenia gravis affects the body by interfering with normal muscle function, causing rapid muscle fatigue. The most commonly affected areas include the eyelid muscles, those responsible for eye movement, facial muscles, those involved in speech, chewing, and swallowing, as well as the muscles of the neck and limbs. In severe cases, it can affect the muscles responsible for breathing, requiring urgent medical intervention.
H2: Types of myasthenia and manifestations
Myasthenia gravis can be classified into several types, the main ones being ocular myasthenia gravis and generalized myasthenia gravis, each with distinct manifestations depending on the muscle groups affected.
H3: Ocular myasthenia gravis
Ocular myasthenia is limited to the muscles that control eye and eyelid movement, causing symptoms such as drooping eyelids (ptosis) and double vision (diplopia). This form may be an early stage of the disease, but in some cases remains localized to the eye.
H3: Generalized myasthenia gravis
Generalized myasthenia gravis affects a wider range of muscles in the body, including those of the face, neck, limbs and, in severe cases, breathing. Manifestations include progressive muscle weakness, difficulty speaking, chewing and swallowing, and a significant decrease in physical capacity. This form may require more complex treatments and careful monitoring.
H2: Causes of myasthenia gravis
Causes of myasthenia gravis include abnormal production of antibodies that block neuromuscular receptors, influence of the thymus gland, and genetic or environmental factors that can trigger or worsen the disease.
H3: The role of the thymus gland and antibodies
The thymus gland plays an important role in the development of myasthenia gravis, because in many patients, it remains abnormally active into adulthood, producing antibodies that attack acetylcholine receptors. In some cases, benign tumors of the thymus (thymoma) may be present, which contribute to the progression of the disease.
H3: Myasthenia gravis and the immune system
Myasthenia gravis is an autoimmune disease, which means that the immune system attacks its own healthy cells. In this case, antibodies produced by the immune system block or destroy acetylcholine receptors at the neuromuscular junction, preventing nerve signals from reaching the muscles.
H3: Genetic and environmental factors
Although myasthenia gravis is not a strictly hereditary disease, genetic predisposition may play a role, especially in combination with other factors. Environmental factors, such as infections, stress, or exposure to certain medications, can also trigger or worsen symptoms of the disease.
H2: Risk factors for myasthenia gravis
Risk factors for myasthenia gravis include demographic characteristics such as age and sex, along with genetic predisposition associated with markers such as the HLA-B27 antigen.
H3: Age and sex
Myasthenia gravis can affect people of all ages, but women are more commonly diagnosed before the age of 40, while men are more likely to develop the disease after the age of 60.
H3: HLA-B27 antigen and other markers
The presence of certain genetic markers, such as the HLA-B27 antigen and other variants of the major histocompatibility complex (MHC), may increase susceptibility to myasthenia gravis, indicating an important role of genetic predisposition in the onset of the disease.
H2: Symptoms of myasthenia gravis
Symptoms of myasthenia gravis include progressive muscle weakness, drooping eyelids, difficulty swallowing and speaking, and in severe cases, life-threatening respiratory complications.
H3: Muscle fatigue and drooping eyelids
One of the most common symptoms is muscle fatigue that worsens with activity and improves with rest, along with drooping eyelids (ptosis), which can affect one or both eyes.
H3: Difficulty swallowing and speaking
Myasthenia gravis can cause difficulty swallowing (dysphagia) and weakness of the muscles involved in speech, leading to slurred or nasal speech, as well as a risk of aspiration.
H3: Respiratory complications and myasthenic crisis
In severe cases, muscle weakness can affect the respiratory muscles, leading to difficulty breathing or acute respiratory failure, known as myasthenic crisis, which requires emergency medical treatment.
H2: How is myasthenia gravis diagnosed?
The diagnosis of myasthenia gravis is based on a detailed clinical examination, blood tests for specific antibodies, thymus imaging, and electromyography to assess neuromuscular function.
H3: Clinical examination and medical history
Diagnosis begins with a detailed clinical examination, in which the doctor analyzes the symptoms, observes the characteristic signs of the disease, such as eyelid ptosis and muscle weakness, and asks the patient about personal and family medical history.
H3: Thymus tests and antibody testing
To confirm the diagnosis, thymus tests are performed using blood tests that detect the presence of antibodies against acetylcholine receptors or other proteins involved in the disease. They can also check for abnormalities in the thymus gland, such as thymoma.
H3: Imaging Tests and Electromyography
Imaging tests, such as computed tomography (CT) or magnetic resonance imaging (MRI), can be used to examine the thymus gland and identify any tumors or abnormalities. Electromyography (EMG) measures the electrical activity of muscles, helping to assess neuromuscular function and confirm the diagnosis.
H2: Treatment of Myasthenia Gravis
Treatment of myasthenia gravis includes drug therapies to control symptoms and physical rehabilitation through physiotherapy, and integrative therapies, such as the HHO® 720° Protocol, can help revitalize the body and improve blood health for a more vital life.
H3: Drug Treatments
Myasthenia gravis doctors, such as neurologists, provide accurate diagnosis and personalized treatment plans for patients. Drug treatment for myasthenia gravis includes the use of cholinesterase inhibitors to improve neuromuscular transmission, immunomodulators to control immune system activity, and, in some cases, corticosteroids and immunosuppressants to reduce inflammation and prevent further muscle damage.
H3: Physiotherapy and rehabilitation exercises
Physiotherapy plays an essential role in the management of myasthenia gravis, helping to maintain muscle tone and improve mobility. Rehabilitation exercises are tailored to the individual needs of the patient, with the aim of reducing fatigue and increasing physical endurance, especially for the muscles that control eye movement, neck and breathing.
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Electrotherapy/ Papimi
H3: Personalized Integrative Therapy
New developments in the treatment of myasthenia gravis include innovative therapies such as the HHO® 720° protocol, which combines advanced techniques for detoxification and cellular regeneration. The HHO® 720° blood health recovery protocol represents a complete commitment to the integral well-being of the individual. At Quantica720°, we approach health as a harmonious whole, focusing on improving blood health and revitalizing the entire body.
The HHO® protocol lasts 3 days and is carried out in three stages: hemoperfusion (advanced blood filtration), hyperthermia (controlled blood heating) and oxygenation (oxygen enrichment of the blood). On the first day, intravenous therapies for chelation and toxin drainage are performed, on the second day, the HHO® procedure is applied, followed by intravenous cocktails for the immune system and mineralization, and on the last day, it is completed with intravenous-electromagnetic procedures for blood alkalization, remineralization and administration of natural antioxidants. This innovative protocol helps eliminate toxins, improve immune system function and restore the overall balance of health.
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H2: Recommended lifestyle for myasthenia gravis
Adopting a healthy lifestyle for myasthenia gravis involves a balanced diet and adequate nutritional support, along with stress management and ensuring adequate rest to support physical and mental health.
Nutritional Consultation Link
H3: Diet and Nutritional Support
A balanced diet tailored to individual needs is essential for patients with myasthenia gravis. Eating foods rich in antioxidants, vitamins and minerals, especially zinc, vitamin D and magnesium, can support the functioning of the immune system and muscles. It is also important to avoid foods that can cause inflammation or imbalances, such as refined sugar and trans fats. Consulting a nutritionist can provide a personalized eating plan to support overall health.
Link Test IGGG/ IGA
H3: Stress Management and Rest
Stress management is crucial in the treatment of myasthenia gravis, as stress can worsen symptoms. Relaxation practices such as meditation, yoga or breathing exercises help reduce tension and improve well-being. Adequate rest is also vital for muscle recovery and maintaining energy; patients should have a regular sleep schedule and avoid physical overexertion.
H2: Conclusion
Myasthenia gravis is a complex but manageable condition, through a combination of medical treatments, integrative therapies and lifestyle adjustments. With a correct diagnosis, a personalized approach and the support of a dedicated medical team, patients can have a significantly improved quality of life. Adopting an integrative perspective that includes physical, mental and nutritional health is essential to support the body in the fight against this disease and to maintain vitality and balance in the long term.
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Bibliography
Jayam Trouth, A., Dabi, A., Solieman, N., Kurukumbi, M., & Kalyanam, J. (2012). Myasthenia gravis: a review. Autoimmune diseases, 2012(1), 874680.
Farmakidis, C., Pasnoor, M., Dimachkie, M. M., & Barohn, R. J. (2018). Treatment of myasthenia gravis. Neurological Clinics, 36(2), 311-337.
Gilhus, N. E., & Verschuuren, J. J. (2015). Myasthenia gravis: subgroup classification and therapeutic strategies. The Lancet Neurology, 14(10), 1023-1036.
Online Articles
https://www.mayoclinic.org/diseases-conditions/myasthenia-gravis/symptoms-causes/syc-20352036 Accessed 01/13/2025
https://my.clevelandclinic.org/health/diseases/17252-myasthenia-gravis-mg Accessed 01/13/2025
https://www.nhs.uk/conditions/myasthenia-gravis/ Accessed 01/13/2025
https://myasthenia.org/understanding-mg/what-is-myasthenia-gravis/ Accessed 01/13/2025
